Post-transplant lymphoproliferative disorder

Abstract

Post-transplant lymphoproliferative disorders (PTLDs) are life-threatening complications of solid-organ transplantation and bone marrow transplantation leading to a high mortality. PTLD represents a heterogeneous group of lymphoproliferative diseases. They become clinically relevant because of the expansion of transplantation medicine together with the development of potent immunosuppressive drugs associated now with long survival. The risk of PTLD is highest in the early post-transplant period, but the cumulative risk increases with time. We report a case of two sequential malignancies – carcinoma bladder occurring -13 years and now gastric lymphoma -15 after renal transplantation in a 73-year-old man.