Comorbidity of Urogynecological and Gastrointestinal Disorders in Female Patients with Lichen Sclerosus

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Abstract

Objective Lichen sclerosus (LS) is a chronic inflammatory disease with a significant impact on quality of life. The aim of this cross-sectional case-control study was to characterize concomitant urogynecological and gastrointestinal disorders in female patients with LS. Methods A medical records search between 2004 and 2012 yielded 455 women and girls (mean age 64 years) with LS. The study cohort was compared with a 10-fold age- and sex-matched control cohort. Gynecological cancers and their precursors; gynecological, urinary, and gastrointestinal disorders; and pain syndromes were evaluated. Results The well-known association between LS and increased risk of vulvar cancer and its precursors was also found in our study (relative risk [RR] = 100.0; p

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Söderlund, J. M., Hieta, N. K., Kurki, S. H., Orte, K. J., Polo-Kantola, P., Hietanen, S. H., & Haataja, M. A. M. (2023). Comorbidity of Urogynecological and Gastrointestinal Disorders in Female Patients with Lichen Sclerosus. Journal of Lower Genital Tract Disease, 27(2), 156–160. https://doi.org/10.1097/LGT.0000000000000727

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