Erradicación del Helicobacter pylori en pacientes obesos pre-cirugía bariátrica

Abstract

Many bariatric surgeons recommend routine Helicobacter pylori (H. pylori) screening as a part of the workup for bariatric surgery. Some studies suggested that obese patients have a lower eradication rate and the Body Mass Index could be independent risk factor for this failure. Objective. To evaluate the H. pylori eradication of a 14 days Quadruple Concomitant therapy in obese patients undergoing bariatric surgery compared against a control group. Material and Methods. Prospective study included 76 patients undergoing bariatric surgery and 75 control patients with a normal BMI and dyspepsia. Results. In the obese group, the eradication rate was 69% whereas in the control group was 89%. p < 0.05, Odds ratio 3.18 (CI 1.35-7.45). The distribution of age, gender, smoking and diabetes did not differ significantly between the two groups. Conclusions. Obese patients showed a significantly lower eradication of H. pylori than controls to a two weeks Quadruple Concomitant therapy.