Live birth following treatment of metastatic cerebral choriocarcinoma

Abstract

Choriocarcinoma is a malignant tumor of trophoblastic tissue and constitutes about 30 to 40% of the trophoblastic neoplasia cases. Early hematogenous spread is characterstic of choriocarcinoma. We report a case of metastatic cerebral choriocarcinoma in a 23-year-old female with appearance of acute neurological signs following spontaneous intracerebral hemorrhage as the initial presentation. She underwent successful treatment of choriocarcinoma with chemotherapy (EMA-CO regime) and was able to have normal baby with good apgar score. The case emphasizes the importance of suspecting an underlying choriocarciroma in women of child bearing age group presenting with spontaneous cerebral hemorrhage and an uncomplicated term delivery can be expected after complete chemotherapy for GTN.