Background: The correlation between levels of Lipoprotein-a, Neutrophil Lymphocyte Ratio and hypertension with clinical severity scale remains a controversial issue. Objective: To determine the correlation of levels of Lipoprotein-a, Neutrophil Lymphocyte Ratio and hypertension with the severity scale measured by NIHSS scale in patients with acute thrombotic stroke. Method: Lipoprotein-a levels, Neutrophil Lymphocyte ratio, blood pressure in patients with acute thrombotic stroke were measured and clinical severity scale was assessed by NIHSS scale. The levels of lipoprotein-a were grouped into normal and high levels of lipoprotein-a, Lymphocyte Neutrophil Ratios were grouped into low and high and hypertension were grouped into stage 1 and 2. The data was analyzed using logistic regression. Results: There were 40 patients consisting of 29 (72.50%) male patients and 11 (27.50%) female patients. The demographic data included gender, age, LDL level, random blood sugar level, diabetes mellitus status and smoking status which were all homogeneous in both groups of lipoprotein-a, Neutrophil Lymphocyte ratio and hypertension stage. In the logistic regression analysis, the lipoprotein-a and neutrophil lymphocyte ratio were correlated with clinical severity scale (p = 0.018, RO 0.122 (CI 95% 0.022-0.696) vs p = 0.041, RO 0.068 (95% CI 0.005-0.895) while hypertension stage was not correlated with clinical severity scale (p = 0.97, RO 1.02 (95% CI 0.28-3.80). Conclusion: The levels of lipoprotein-a and lymphocyte neutrophil ratio were related to the clinical severity measured by NIHSS scale but not with hypertension.
CITATION STYLE
Mahfoed, M. H., Hamdan, M., Sugianto, P., Sani, A. F., Ardhi, M. S., Fadil, & Hunaifi, I. (2020). The association of lipoprotein-a levels, neutrophil lymphocyte ratio and hypertension with the clinical severity scale measured by nihss scale in patients with acute thrombotic stroke. Medico-Legal Update, 20(2), 658–663. https://doi.org/10.37506/mlu.v20i2.1187
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