YM-266183 and YM-266184, novel thiopeptide antibiotics produced by Bacillus cereus isolated from a marine sponge. II. Structure elucidation

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Abstract

YM-266183 and YM-266184 are new antibacterial substances that have activity against drug-resistant bacteria produced by Bacillus cereus QN03323. These structures were elucidated by MS and NMR spectral analysis. YM-266183 and YM-266184 are the cyclic thiopeptides containing thiazole and pyridine moieties, and several unusual amino acids.

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Suzumura, K. I., Yokoi, T., Funatsu, M., Nagai, K., Tanaka, K., Zhang, H., & Suzuki, K. (2003). YM-266183 and YM-266184, novel thiopeptide antibiotics produced by Bacillus cereus isolated from a marine sponge. II. Structure elucidation. Journal of Antibiotics, 56(2), 129–134. https://doi.org/10.7164/antibiotics.56.129

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