Progressive multifocal leukoencephalopathy (PML) presenting as intractable dystonia in an HIV-infected child

Abstract

Progressive multifocal leukoencephalopathy (PML) has been described in adult immunocompromised patients and has a progressive downhill course. Though dementia and motor disturbances have been described, intractable dystonia is a very unusual manifestation. In children, PML is very rare and often misdiagnosed as other central nervous system (CNS) encephalopathy. No definitive treatment is available. © The Author [2005]. Published by Oxford University Press. All rights reserved.