Anti-inflammatory activity of leaf of Melastoma malabathricum L. (Melastomataceae)

Abstract

In the present study, Melastoma malabathricum leaf was extracted with ethanol and evaluated for anti-inflammatory activity in rats using a carrageenan induced paw edema method. Ethanol extract exhibits potent anti-inflammatory activity at 500mg/kg at 3hr after administration. The study was compared with standard drug indomethacin (10mg/kg). Observed pharmacological activity in the present study provides scientific validation of ethnomedicinal uses of this plant in treating acute inflammation.