Syntheses of chiral β- And γ-amino ethers, morpholines, and their homologues via nucleophilic ring-opening of chiral activated aziridines and azetidines

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Abstract

99%, de up to 99%). The methodology was further extended to synthesize morpholines and their homologues with high enantiospecificity (ee up to 90%) when halo alcohols were employed as the nucleophiles. © 2012 American Chemical Society.

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Ghorai, M. K., Shukla, D., & Bhattacharyya, A. (2012). Syntheses of chiral β- And γ-amino ethers, morpholines, and their homologues via nucleophilic ring-opening of chiral activated aziridines and azetidines. Journal of Organic Chemistry, 77(8), 3740–3753. https://doi.org/10.1021/jo300002u

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