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The colorectal cancer immune paradox revisited

OncoImmunology (2016) 5(2)
DOI: 10.1080/2162402X.2015.1078058
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Abstract

Tumor infiltrating lymphocytes (TILs) represent a strong independent predictor of relapse and overall survival in colorectal cancer (CRC). However, it appears that a majority of CRCs, i.e., microsatellite stable (MSS) tumors, are refractory to immune checkpoint blockers. The results of recent comprehensive analyses of genomic data provide possible answers.

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Angelova, M., Charoentong, P., Hackl, H., & Trajanoski, Z. (2016). The colorectal cancer immune paradox revisited. OncoImmunology, 5(2). https://doi.org/10.1080/2162402X.2015.1078058

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