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Fatty acid metabolism meets organelle dynamics

Developmental Cell
DOI: 10.1016/j.devcel.2015.03.008
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Abstract

Upon nutrient deprivation, cells metabolize fatty acids (FAs) in mitochondria to supply energy, but how FAs, stored as triacylglycerols in lipid droplets, reach mitochondria has been mysterious. Rambold etal. (2015) now show that FA mobilization depends on triacylglycerol lipolysis, whereas autophagy feeds the lipid droplet pool for continued fueling of mitochondria.

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Walch, L., Čopič, A., & Jackson, C. L. (2015, March 23). Fatty acid metabolism meets organelle dynamics. Developmental Cell. Cell Press. https://doi.org/10.1016/j.devcel.2015.03.008

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