Short term clinical and echocardiography outcomes of pericardiectomy in constrictive pericarditis

Abstract

Introduction: Tuberculous pericarditis continues to be a leading cause of chronic constrictive pericarditis (CCP) in developing countries. Echocardiography plays a key role in the assessment and diagnosis. Methods: Twelve patients who underwent pericardiectomy for CCP in last 18 months of the study period were subjected to clinical and New York Heart Association (NYHA) functional class assessment along with comprehensive echocardiographic evaluation. The data were compared with their pre-procedural status. Results: Significant reduction was noted in the incidence of inferior vena cava (IVC) congestion (P < 0.001) and mean left atrial (LA) size from 43.75 ± 4.43 mm to 31.58 ± 3.03 mm (P < 0.001), post-pericardiectomy. Respiratory variation of 34.17 ± 8.76 % in the mitral E velocity was significantly reduced to 17 ± 3.69 % (P < 0.001) after surgery. Similarly, respiratory variation in tricuspid E velocities showed significant reduction from 62.17 ± 13.16 % to 32.58 ± 4.7 % (P < 0.001). Prior to pericardiectomy, medial e' and lateral e' mitral annular velocities was 15.5 ± 1.24 cm/sec and 13.08 ± 1.08 cm/sec, respectively. Following surgery, the medial e' and lateral e' was 12.5 ± 1.17 cm/sec (P = 0.001) and 15.42 ± 1.83 (P = 0.004), respectively. Conclusion: Echocardiography provides useful insight in pericardial constriction hemodynamics and worthwhile effects of pericardiectomy.