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A family study of dentinogenesis imperfecta shields type II caused by a novel DSPP mutation and investigations on the isolated stem cells from human exfoliated deciduous teeth

BMC Oral Health (2025) 25(1)
DOI: 10.1186/s12903-025-05912-8
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Abstract

This study provides insights into the genetic and cellular basis of DGI-II, elucidating the role of a novel DSPP mutation in tooth structure development and stem cell behavior. However, in vivo validation of this DSPP mutation is important to further confirm this conclusion.

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Gao, Q., Yue, N., Liu, K., Deng, Z., Yang, L., Zou, J., & Du, Q. (2025). A family study of dentinogenesis imperfecta shields type II caused by a novel DSPP mutation and investigations on the isolated stem cells from human exfoliated deciduous teeth. BMC Oral Health, 25(1). https://doi.org/10.1186/s12903-025-05912-8

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