This artice is free to access.
Objectives: We study the optimal control strategy for the effects of hard water consumption on kidney-related diseases. The mathematical model has been formulated and studied to gain insights on the optimal control strategy on the effects of hard-water consumption on kidney-related diseases. The positivity and boundedness of the solutions are determined. A global sensitivity analysis has been performed and the numerical solutions have been carried out. Results: A global sensitivity analysis shows that the control on water is an important parameter. This can reduce the proportion of individuals with kidney-dysfunction and hence reduces the proportion of individuals with kidney-related diseases. Furthermore, the numerical solutions show that with the optimal control, the proportion of individuals with kidney-related diseases can be minimised.
Ndii, M. Z., Berkanis, F. R., Tambaru, D., Lobo, M., Ariyanto, & Djahi, B. S. (2020). Optimal control strategy for the effects of hard water consumption on kidney-related diseases. BMC Research Notes, 13(1). https://doi.org/10.1186/s13104-020-05043-z