Antioxidant and antimicrobial activities in leaf methanolic extracts from the plant genus Solanum

Abstract

The present research study assessed antioxidant and antimicrobial activities in leaf methanolic extracts from ten plant species of the genus Solanum. Antioxidant activity (phenol content and total flavonoids) was determined by using in vitro models. The presence of total phenols was evaluated by high-performance liquid chromatography. Antimicrobial activity was examined by using the microorganisms Klebsiella pneumoniae, Staphylococcus aureus, and Escherichia coli. The results showed variations in total phenol content (54 to 286 mg eq. gallic Ac/g) and total flavonoids (18 to 73 mg eq. quercetin/g). There were variations in anti-radical DPPH activity (0.01 to 5.2 μmol eq. Trolox/100 g), ABTS + (0.03 to 2.01-μmol eq. Trolox/100 g), and FRAP reducer (202 to 887 μmol eq. Ac. ascorbic/g). Both S. mammosum and S. barbeyanum extracts showed antimicrobial activity against Escherichia coli. It is concluded that the S. mammosum extract is a major source of bioactive compounds.