Base-promoted SNAR reactions of fluoro- And chloroarenes as a route to N-aryl indoles and carbazoles

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Abstract

KOH/DMSO-promoted C-N bond formation via nucleophilic aromatic substitution (SNAr) between chloroarenes or fluoroarenes with indoles and carbazole under transition metal-free conditions affording the corresponding N-arylated indoles and carbazoles has been developed.

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Iqbal, M. A., Mehmood, H., Lv, J., & Hua, R. (2019). Base-promoted SNAR reactions of fluoro- And chloroarenes as a route to N-aryl indoles and carbazoles. Molecules, 24(6). https://doi.org/10.3390/molecules24061145

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