Formulation and evaluation of herbal anti-inflammatory Emulgel prepared from Vitex neugondo leaves extract

Abstract

Topical drug delivery system is dosage forms which are applied directly to skin to cure various disease. In comparison with the other semisolid formulation the use of gel seen to be more advantages both in cosmetics and pharmaceutical preparation. Emulgel have emerged as a promising drug delivery system for the delivery of hydrophobic drugs. The objective of the study was to prepare from the leaves of Vitex negundo plant using Carbopol 940 as a gelling agent. Eucalyptus oil and menthe oil were used as penetration enhancers. Propylene glycol amount of distilled water. The skin pH was maintained by addition of tri-ethanolamine. The formulation was evaluated for spread ability, Viscosity, in vitro release drug content pH, physical stability etc. On this experimental work prevalent that the herbal gel of leaves extract from leaves of Vitex negundo found good gelling property and it will be useful as anti-inflammatory gel as per the literature.