The effectiveness and safety of convalescent plasma as therapy for COVID-19 patients: A literature review

Abstract

COVID-19 is a new disease caused by SARS-CoV-2 with an increasing number of cases. until now, no specific vaccine or antiviral therapy regimen has yet been found. A therapy that has been known for approximately a century ago called convalescent plasma therapy has been discussed again as an effective and safe therapy for COVID-19 patients. Conduct a literature review of scientific studies related to the effectiveness and safety of convalescent plasma as a therapy for COVID-19 patients. Convalescent plasma has proven to be effective because it can improve the clinical condition felt by patient, prevent the entry of viruses into cells and inhibit the virus replication. This therapy is also proven to have no harmful effects, so it is safe to be performed by paying attention to certain things such as conditions that must be fulfilled by the donors.