Methicillin-resistant Staphylococcus aureus bacteremia with elevated vancomycin minimum inhibitory concentrations

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Abstract

This case-control study of 25 cases with methicillin-resistant Staphylococcus aureus (MRSA) bacteremia with vancomycin minimum inhibitory concentration (MIC) ≥ 2 g/mL and 391 controls (MIC < 2 g/mL) characterized the clinical characteristics, treatments, and outcomes associated with elevated vancomycin MIC. Elevated vancomycin MIC was associated with baseline hemodialysis, prior MRSA colonization, and metastatic infection.

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Mills, A. G., Dupper, A. C., Chacko, K. I., Alburquerque, B., Nadkarni, D., Berbel Caban, A., … Altman, D. R. (2023). Methicillin-resistant Staphylococcus aureus bacteremia with elevated vancomycin minimum inhibitory concentrations. Antimicrobial Stewardship and Healthcare Epidemiology, 3(1). https://doi.org/10.1017/ash.2023.163

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