Identification of the ahp operon of Salmonella typhimurium as a macrophage-induced locus

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Abstract

Previously, we tagged a macrophage-induced Salmonella typhimurium locus with Mudlux (K. P. Francis and M.P. Gallagher, Infect. Immun. 61:640-649, 1993). The insertion lies within the OxyR-regulated ahpC locus and conveys alkyl peroxide sensitivity. Plasmid-encoded ahp reverses sensitivity but reduces luminescence. This suggests that OxyR is titrated by the multicopy ahp promoter.

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Francis, K. P., Taylor, P. D., Inchley, C. J., & Gallagher, M. P. (1997). Identification of the ahp operon of Salmonella typhimurium as a macrophage-induced locus. Journal of Bacteriology, 179(12), 4046–4048. https://doi.org/10.1128/jb.179.12.4046-4048.1997

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