Platycoside N: A new oleanane-type triterpenoid saponin from the roots of platycodon grandiflorum

Abstract

A new oleanane-type triterpenoid saponin, named platycoside N (1), together with six known saponins, was isolated from the roots of Platycodon grandiflorum. On the basis of acid hydrolysis, comprehensive spectroscopic data analyses and comparison with the spectral data of the known compounds, its structure was elucidated as 3-O-β-Dglucopyranosyl-( 1→6)-β-D- glucopyranosyl-2β,3β,16α,23-tetrahydroxyolean-12-en-28-oic acid 28-O-β-L-rhamnopyranosyl-(1→2)-α-L-arabinopyranoside. The six known compounds were platycodin D (2), deapioplatycodin D (3), platycodin D 3 (4), deapioplatycodin D3 (5), platycoside E (6) and deapioplatycoside E (7). © 2010 by the authors; licensee MDPI, Basel, Switzerland.