Shapiro and Bamford-Stevens reactions - revisited

Abstract

The Shapiro as well as the Bamford-Stevens reactions are very convenient methods for preparing numerous olefinic compounds from ketones and aldehydes via sulfonylhydrazones. These reactions allow preparation not only simple molecules with a double bond but also larger, complex systems that could have biological activity. Therefore, the synthetical aspects of above-mentioned reactions are of broad interest to organic chemists. This mini review describes the application of Shapiro as well as Bamford-Stevens reactions in the preparation of olefinic compounds.