Characterization of bioactive glass synthesized by sol-gel process in hot water

Abstract

Bioactive glass 70SiO2-30CaO (mol.%) was successfully synthesized by modified sol–gel in hot water without using an acid catalyst. TG-DSC analysis showed that the amorphous glass could be synthesized by sintering the sample at 700◦ C for three hours. The N2 adsorption/desorption and TEM investigations highlighted that the synthetic glass had a mesoporous structure, consisting of spherical particles with sizes in the range of 11–20 nm. The specific surface area, pore volume, and average pore diameter of synthetic glass were 150.13 m2 /g, 0.37 cm3 /g, and 11.84 nm, respectively. Moreover, synthetic bioactive glass presented interesting bioactivity and good biocompatibility after in vitro experiments in simulated body fluid (SBF) and in cellular medium.