Lack of uptake of catecholamines after chronic denervation of sympathetic nerves

Abstract

DENERVATION of sympathetically innervated structures has been known to cause supersensitivity of these organs to catecholamines1 and depletion of these hormones2. However, no conclusive explanation has been offered for these findings. To clarify these phenomena further we compared the uptake of injected DL β-3H-noradrenaline and DL β- 3H-adrenaline by intact and denervated tissue. © 1961 Nature Publishing Group.