Maternal and Perinatal Outcome in Dengue Fever in Pregnancy in North India

Abstract

Aim and objective: The aim and objective of the study was to assess the maternal and neonatal complications in all the cases of dengue fever in pregnancy. Materials and methods: This was a prospective observational study of pregnant and postpartum women with dengue hemorrhagic fever. Results: Postpartum hemorrhage (PPH) was reported in 35/195 (18%); PPH occurred due to severe thrombocytopenia, atonic uterus, and deranged coagulopathy. Other complications seen were antepartum hemorrhage such as abruption (11.7%), preeclampsia (3.5%), and eclampsia (0.5%). Seven cases of dengue were seen in the first and early second trimesters and two of these had miscarriages. Oligohydramnios was reported in 21%, preterm birth in around one-fourth of the patients. Majority of the patients (80%) presented with thrombocytopenia. Around half (46%) pregnant women in late second and third trimesters presented without any complications. Conclusion: Dengue fever in pregnancy leads to adverse maternal and perinatal outcomes including PPH, preterm labor, oligohydramnios, and intrauterine fetal deaths.