Selenium-mediated synthesis of tetrasubstituted naphthalenes through rearrangement

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Abstract

New β-keto ester substituted stilbene derivatives have been synthesized and cyclized with selenium electrophiles in the presence of Lewis acids. This now allows access to 1,2,3,4-tetrasubstituted naphthalene derivatives as cyclization and rearrangement products.

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Tancock, J., & Wirth, T. (2015). Selenium-mediated synthesis of tetrasubstituted naphthalenes through rearrangement. Molecules, 20(6), 10866–10872. https://doi.org/10.3390/molecules200610866

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