Scope of the suzuki-Miyaura cross-coupling reactions of potassium heteroaryltrifluoroborates

Abstract

A wide variety of bench-stable potassium heteroaryltrifluoroborates were prepared, and general reaction conditions were developed for their cross-coupling to aryl and heteroaryl halides. The cross-coupled products were obtained in good to excellent yields. This method represents an efficient and facile installation of heterocyclic building blocks onto preexisting organic substructures. © 2009 American Chemical Society.