Synthesis and properties of O-β-D-ribofuranosyl-(1″ → 2′)-guanosine-5″-O-phosphate and its derivatives

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Abstract

The efficient synthesis of O-β-D-ribofuranosyl-(1″ → 2′)-guanosine-5″-O-phosphate and O-β-D-ribofuranosyl-(1″ → 2′)-adenosine-5″-O-phosphate, minor tRNA components, have been developed, and their conformational properties were examined by NMR spectroscopy.

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Efimtseva, E. V., Shelkunova, A. A., Mikhailov, S. N., Nauwelaerts, K., Rozenski, J., Lescrinier, E., & Herdewijn, P. (2003). Synthesis and properties of O-β-D-ribofuranosyl-(1″ → 2′)-guanosine-5″-O-phosphate and its derivatives. Helvetica Chimica Acta, 86(2), 504–514. https://doi.org/10.1002/hlca.200390050

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