Improved Production of Gibberellic Acid by Fusarium moniliforme

Abstract

Optimization studies for improvement in the yield of gibberellic acid production by Fusarium moniliforme in submerged and solid-state fermentation is the focus of this paper. In the current study, use of jatropha seed cake as substrate for solid-state fermentation resulted in an unprecedented gibberellic acid yield of 105 mg/g of moldy bran. A 2.5 fold increased in the titre resulting in 15 g gibberellic acid /L could also be obtained by optimization of physiological parameters in submerged fermentation. This is the first study reporting such high yield of gibberellic acid and presenting a commercially viable production process using cheap substrates.