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Assessment of the Hemophagocytic Lymphohistiocytosis HScore in Patients with Coronavirus Disease 2019

Clinical Infectious Diseases (2021) 73(9) E3110-E3112
DOI: 10.1093/cid/ciaa1463
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Abstract

The clinical manifestation of moderate to severe coronavirus disease 2019 (COVID-19) has parallels to secondary hemophagocytic lymphohistiocytosis (HLH) both clinically and based on molecular inflammatory response. We found no evidence to support the utility of risk-stratifying COVID-19 patients using risk scoring methodology designed for HLH.

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Clark, K. E. N., Nevin, W. D., Mahungu, T., Lachmann, H., & Singh, A. (2021). Assessment of the Hemophagocytic Lymphohistiocytosis HScore in Patients with Coronavirus Disease 2019. Clinical Infectious Diseases, 73(9), E3110–E3112. https://doi.org/10.1093/cid/ciaa1463

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