The Central Cattle Breeding and Dairy Farm, Bangladesh waste contributes in emergence and spread of aminoglycoside-resistant bacteria

Abstract

Aminoglycosides are one of the categories of antibiot- ics most frequently used in treating several cattle diseases at the Central Cattle Breeding and Dairy Farm (CCBDF), Savar, Dhaka, Bangladesh. Un- treated veterinary clinical healthcare waste (VCHW) of diseased cattle at CCBDF which directly disposed to surrounding may contribute to the antibiotic resis- tant bacteria pollution (ARB) pollution. The investi-gation analyses the role of VCHW of CCBDF in spreading ARB. Here we studied：1) veterinary clini- cal data and antibiotics treatment history; 2) total and resistant bacteria counts in fecal samples of heal- thy and diseased cattles as well as VCHW of CCBDF; and 3) finally, data analysis to estimate the burden of VCHW of CCBDF in the pollution of environment with aminoglycoside antibiotics resistant bacteria. The results conclusively demonstrate the spread of 3 different aminoglycoside antibiotics, namely genta- mycin, kanamycin and streptomycin resistant bacte- ria in the surrounding environment alarmingly with high significant value (p < 0.01 - 0.05). This study re- veals the risks to the cattle as well as public health posed by the random VCHW disposal at the CCBDF, Bangladesh.