SYNTHESIS, CHARACTERIZATION AND ANTIBACTERIAL ACTIVITY OF SOME IMINE ANALOGS

Abstract

A series of imine analogs were synthesized by the condensation of 3-methoxy 4-hydroxy benzaldehyde with substituted amines in ethanol. The structures of newly synthesized compounds were characterized by IR and 1 HNMR spectroscopy. The purity of the synthesized imines analogs has been ascertained by thin layer chromatography using an acetone-n-hexane mixture (1:3). Antibacterial activity of imines was tested against a panel of sensitive and resistant Gram-positive and Gram-negative strains using disc diffusion assay.