Molecular Weight Determination of Relevant Organometallic Catalysts in Solution by DOSY-NMR to Monitor Reactivity

Abstract

The study of composition, aggregation, or solvation of reactive molecules in solution is of fundamental interest for the classification of reaction mechanisms or the estimation of reactivities. In the past, methodologies have already been presented to make organolithium compounds accessible to a DOSY-NMR-based molecular weight determination. However, complexes with heavy atoms, such as transition metals, were excluded from this because of their elevated van der Waals density. In this publication, we show that our heavy-atom correction based on the external calibration curve data is also suitable for addressing such complexes.