Abstract
We compared pathogen detection between saliva, nasopharyngeal and oropharyngeal swabs in children with respiratory symptoms. The sensitivity in nasopharyngeal swabs was 93% (95% confidence interval [CI]: 78%-98%), in oropharyngeal swabs 79% (95% CI: 60%-90%), in saliva overall 76% (95% CI: 58%-88%) and in 18 saliva samples collected with drooling or sponges, 94% (95% CI: 74%-99%). Saliva could be a relevant specimen alternative.
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De Koff, E. M., Euser, S. M., Badoux, P., Sluiter-Post, J., Eggink, D., Sanders, E. A. M., & Van Houten, M. A. (2021). Respiratory Pathogen Detection in Children: Saliva as a Diagnostic Specimen. Pediatric Infectious Disease Journal, 40(9), E351–E353. https://doi.org/10.1097/INF.0000000000003191
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