The Tla region of the mouse: Identification of a new serologically defined locus, Qa-2

Abstract

In cytotoxicity assays, the reactions of cells from two new congenic strains-B6.K1 and B6.K2-with antiserum prepared in B6.K1 against B6 (C57BL/6) spleen and lymph node cells identify a new locus, Qa-2, between H-2D and Tla. This locus specifies differentiation antigens on lymphoid cells. Skin grafting of B6.K1, B6.K2, and other congenic strains on a B6 background also reveals two histocompatibility loci in the region of Tla. © 1976 Springer-Verlag New York Inc.