Decrease in human immunodeficiency virus type 1 load during acute dengue fever

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Abstract

Rather than the expected increase in human immunodeficiency virus type 1 (HIV-1) load, there was transient suppression of HIV-1 replication during acute dengue infection in a 29-year-old Thai woman. Acute-phase (but not convalescent-phase) serum samples obtained from an HIV-1-uninfected patient with dengue fever reduced HIV-1 infectivity, as determined by a peripheral blood mononuclear cell assay, suggesting the possibility that HIV-1 replication is suppressed during acute dengue fever, as occurs during some cases of scrub typhus infection and measles.

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Watt, G., Kantipong, P., & Jongsakul, K. (2003). Decrease in human immunodeficiency virus type 1 load during acute dengue fever. Clinical Infectious Diseases, 36(8), 1067–1069. https://doi.org/10.1086/374600

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