Potential of methanol extract from the stem bark of mangrove Rhizophora mucronata against bacteria Escherichia coli and Aeromonas hydrophylla

Abstract

Escherichia coli and Aeromonas hydrophylla are well known pathogenic bacteria causing diseases in both human and animals. Since the popular antibacterial drugs in the market lead to resistance, other alternatives antibacterial need to be searched from the active ingredient found in marine and terrestrial vegetation. The potential use of secondary metabolites from marine vegetation is currently being developed. One of marine vegetation that has been expected to have antibacterial activity is mangrove. This study aims to provide information related to the phytochemical and antibacterial activity of methanol extract of the bark of mangrove Rhizophora mucronata. The phytochemical screening and disc testing methods were used in this study. The results showed that the methanol extract of R. mucronata containedphenolics, alkaloids, and terpenoids. Furthermore, the positive outcome of active antibacterial potential of the methanol extract against E. coli and A. hydrophilla has been indicated by inhibition of discs in a clear zone at 7,56 and 7,00 mm.