Small-cell neuroendocrine tumors: Cell state trumps the oncogenic driver

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Abstract

Small-cell neuroendocrine cancers often originate in the lung but can also arise in the bladder or prostate. Phenotypically, small-cell carcinoma of the bladder (SCCB) shares many similarities with small-cell lung cancer (SCLC). It is unknown whether SCCB and SCLC share common genetic driver mutations.

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Oser, M. G., & Janne, P. A. (2018). Small-cell neuroendocrine tumors: Cell state trumps the oncogenic driver. Clinical Cancer Research, 24(8), 775–1776. https://doi.org/10.1158/1078-0432.CCR-17-3646

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