Abstract
Dihydroquercetin (DHQ) is a bioflavonoid with high antioxidant, capillary-protective, and anti-inflammatory activity. DHQ has previously been used for treating Middle East respiratory syndrome coronavirus (MERS-CoV) infection and is currently considered a potential regulator of oxidative stress as part of COVID-19 multipurpose therapy. DHQ has a high safety profile but low bioavailability that limits its use. Innovative techniques (liposomization, crystal engineering, etc.) can be used to increase its bioavailability.
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Orlova, S. V., Tatarinov, V. V., Nikitina, E. A., Sheremeta, A. V., Ivlev, V. A., Vasil’ev, V. G., … Goryainov, S. V. (2022, February 1). Bioavailability and Safety of Dihydroquercetin (Review). Pharmaceutical Chemistry Journal. Springer. https://doi.org/10.1007/s11094-022-02548-8
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