Syntheses of biliverdin derivatives sterically locked at the CD-ring components

Abstract

Total syntheses of biliverdin derivatives with a Z-syn, Z-anti, or E-syn CD-ring components were accomplished via new and efficient methods for the construction of sterically locked CD-ring components towards the elucidation of the stereochemistry of the chromophore in phytochromes. © 2006 The Chemical Society of Japan.