Effect of preservation on the efficacy of terbutaline nebuliser solution in atopic asthma

Abstract

The efficacy of bronchodilator nebuliser solutions may be influenced by the presence of perservatives. In a double blind, randomised, crossover study the effect of preservatives in determining the airway response to 5 mg of terbutaline was studied in a group of 21 atopic asthmatic patients. The presence of preservatives affected neither the bronchodilator action of terbutaline nor its protection against bronchoconstriction induced by histamine.