Oral dextrose gel for hypoglycemia in a well-baby nursery: a baby-friendly initiative

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Abstract

Objectives: To assess the impact of oral dextrose gel (ODG) treatment on NICU admission rates for hypoglycemic infants in a well-baby nursery. Study design: We retrospectively compared newborn infants at risk for hypoglycemia born during the intervention period (n = 3775) with historical controls (n = 655). We also compared the rates of the primary outcome (NICU admission) and secondary outcomes (exclusive breastfeeding and hospital costs) between the two periods. Results: Following the implementation of ODG supplementation, the NICU admissions rates dropped from 4% to 2%, p < 0.05, for at-risk infants and from 15% to 7%, p < 0.05, for hypoglycemic infants in the baseline and intervention periods, respectively, with an adjusted OR (95% CI) of 0.39 (0.24–0.64), p < 0.001. Additionally, the ODG protocol sustained rates of exclusive breastfeeding in contrast to the institutional protocol. Conclusion: The adoption of an ODG protocol fosters a more nurturing and baby-friendly environment through reduced NICU transfers, support for exclusive breastfeeding, and decreased hospital costs.

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APA

Batra, M., Ikeri, K., Blake, M., Mantell, G., Bhat, R., & Zayek, M. (2025). Oral dextrose gel for hypoglycemia in a well-baby nursery: a baby-friendly initiative. Journal of Perinatology, 45(10), 1345–1351. https://doi.org/10.1038/s41372-024-02114-y

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