Working Memory and Functional Neuroimaging in Patients with Depression

Abstract

Numerous studies have demonstrated that patients suffering from depression present impairment in working memory. This paper firstly introduced the concept of working memory, and then elucidated the deficits of working memory of patients with depression. It also reviewed the neuroimaging studies of working memory in patients with depression. In the final part, we further summarized the future research orientations. In short, exploration of working memory on the regulative mechanisms of depression and figuring out that working memory impairment is the cause or the result of depressive symptoms will be the core problem that the future research needs to address.