Clinical application of CLSM, dermoscope and Wood’s lamp in diagnosis and differential diagnosis of five hypopigmentation disorders

Abstract

Objective: To observe the characteristics of hypopigmentation diseases by using confocal laser scanning microscopy (CLSM), dermoscope, and Wood’s lamp. Materials and Methods:This study was conducted at the Affiliated Hospital of ***, from January 2019 to January 2021. We found 397 patients with vitiligo, nevus anemicus, achromic nevus, pityriasis alba, and senile leukoderma, and used CLSM, dermoscope, and Wood’s lamp to analye their characteristics and the differences betweem them. Results: In different kind of hypopigmentation disease, there were different characteristics of CLSM, dermoscope, and Wood’s lamp. And these non-invasive examinations were conducive to diagnose and differentiate hypopigmentation diseases. Conclusion: CLSM, dermoscope, and Wood’s lamp can be used to help the diagnosis and identification of vitiligo, nevus anemicus, achromic nevus, pityriasis alba, and senile leukoderma.