News FLASH-RT: To treat GBM and spare cognition, fraction size and total dose matter

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Abstract

106 Gy/second) FLASH radiotherapy (FLASH-RT) delivery of radiation reduces normal tissue damage without compromising tumor response. Orthotopic glioblastoma mouse studies now demonstrate that radiation fraction size, total dose, and number of fractions are critical parameters for FLASH-RT cognitive sparing without compromising tumor response.

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Huang, C. C., & Mendonca, M. S. (2021). News FLASH-RT: To treat GBM and spare cognition, fraction size and total dose matter. Clinical Cancer Research, 27(3), 662–664. https://doi.org/10.1158/1078-0432.CCR-20-4067

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