Introduction: We present a data analysis and review of recent studies regarding the laboratory diagnosis of human T-lymphotropic virus 1 and 2 (HTLV-1/2) infections in Brazil. Methods: Target populations, available diagnostic serological assays (screening and complementary tests), molecular assays (in-house), causes of false-positive and false-negative results, and flowcharts were analyzed. Results: A table presents the target populations, two diagnostic flowcharts (depending on laboratory infrastructure and study population), and recent research that may improve how HTLV-1/2 is diagnosed in Brazil. Conclusions: Our results support the implementation of public policies to reduce HTLV-1/2 transmission and its associated diseases.
CITATION STYLE
Caterino-De-araujo, A., Barbosa-Stancioli, E. F., Neto, J. B. A., Aragón, M. G., Galvão-Castro, B., Ishak, R., & Rosadas, C. (2021). Laboratory diagnosis of human t-lymphotropic virus in brazil: Assays, flowcharts, challenges, and perspectives. Revista Da Sociedade Brasileira de Medicina Tropical, 54. https://doi.org/10.1590/0037-8682-0175-2021
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