Chemical composition and antibacterial properties of achillea micrantha

Abstract

The composition of detectable small organic compounds in the ethanol extract of Achillea micrantha was defined by means of gas chromatography-mass spectrometric analysis. There were 71 low molecular weight organic compounds observed, two of which remained unidentified. The antibacterial activity of the extract was studied in respect to Escherichia coli, Staphylococcus aureus, Pseudomonas aeruginosa using the agar diffusion test and serial dilutions to define minimum inhibitory concentration. In order to compare the antibacterial activity of the herb and blossom truss extract of Achillea micrantha, the extracts of Achillea millefolium and Achillea leptophylla was used. In relation to the microorganisms tested, a significant inhibitory effect was observed with the aqueous alcoholic extract of Achillea micrantha at the minimum inhibitory concentration of 0.05 µg/ml.