In vitro activity of a new polyene, SPA-S-843, against yeasts

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Abstract

The in vitro activity of a new water-soluble polyene, SPA-S-843, was evaluated against 116 strains of Candida, Cryptococcus, and Saccharomyces spp. and compared with that of amphotericin B. SPA-S-843 demonstrated better inhibitory activity against all of the yeasts examined and better fungicidal activity against Candida albicans, Candida glabrata, Candida krusei, and Candida tropicalis than did amphotericin B.

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Rimaroli, C., & Bruzzese, T. (1998). In vitro activity of a new polyene, SPA-S-843, against yeasts. Antimicrobial Agents and Chemotherapy, 42(11), 3012–3013. https://doi.org/10.1128/aac.42.11.3012

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