Gas chromatographic-electron capture detection method for determination of 29 organochlorine pesticides in finished drinking water: collaborative study.

Abstract

A joint U.S. Environmental Protection Agency/AOAC interlaboratory method validation study was conducted on EPA Method 508, Determination of Chlorinated Pesticides in Water by Gas Chromatography with an Electron Capture Detector, to determine the mean recovery and precision for analyses of 29 pesticides in reagent water and finished drinking water. The study design was based on Youden's nonreplicate plan for collaborative tests of analytical methods. The waters were spiked with 29 pesticides at 6 concentration levels, as 3 Youden pairs. Eleven volunteer laboratories extracted the spiked test waters with methylene chloride, performed a solvent exchange with methyl tert-butyl ether, and analyzed an aliquot of each extract by gas chromatography with electron capture detection. Results were analyzed using an EPA computer program, interlaboratory Method Validation Study (IMVS), which measured recovery and precision for each of the 29 pesticides and compared the performance of the method between water types. Method 508 was judged acceptable for all analytes tested. Only 3 analytes (alpha-chlordane, 4,4'-DDE, and methoxychlor) exhibited practical significant matrix effects. The method has been adopted official first action.