Beyond reproduction: The ovary as a systemic regulator of female health and aging

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Abstract

Classifying ovaries solely as reproductive organs has obscured their role as systemic regulators of female physiology. This Perspective makes the case that ovarian aging is a primary determinant of healthspan and belongs at the center of geroscience.

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Garrison, J. L. (2026). Beyond reproduction: The ovary as a systemic regulator of female health and aging. PLoS Biology, 24(5), e3003800. https://doi.org/10.1371/journal.pbio.3003800

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